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Symptoms of Deadly Whooping Cough After UK Outbreak Kills 11 Babies

AP 4 DEC 2025

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A breakthrough new vaccine spray could be the first to stop spread of the deadly whooping cough infection, which causes infants to turn blue, after a horror outbreak

A new vaccine is being developed against whooping cough after a devastating outbreak killed 11 babies.

It comes after Britain was hit by the worst outbreak in 40 years during 2024 as patients reported violent coughing fits that proved dangerous to the young and elderly. To stop a similar outbreak taking hold again the Government is launching a national clinical trial to develop a nasal spray which would be the first vaccine which can stop whooping cough bacteria from living in the nose and throat.

Initial trials of the new vaccine, called BPZE1, show it appears to stop the spread of infection. Currently, the NHS offers an injectable vaccine to pregnant women to protect babies in the womb but this cannot stop people from carrying and spreading the bacteria.

Whooping cough spreads very easily and there were around 15,000 cases reported in England in 2024. Last years outbreak killed 11 babies. A further 11 deaths occurred in older individuals, most aged over 60 years and all with more than one cause of death documented.

People who catch whooping cough are contagious for up to three weeks after the coughing starts.

Early Signs

The first signs of infection are similar to a cold, such as a runny nose and sore throat, but after about a week, the infection can develop into coughing bouts that last for a few minutes and are typically worse at night.

Young babies may also make a distinctive whoop a gasp for breath between coughs.

But some adults and young babies do not make this noise which can make the condition harder to recognise.

Danger Stage

Difficulty breathing is the danger and for infants there is a risk of stopping breathing entirely.

The NHS website says children may have difficulty breathing after a coughing bout and may turn blue or grey young infants. It also warns that sufferers may bring up a thick mucus, which can make you vomit

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Babies under 12 months old with whooping cough have an increased chance of having problems such as dehydration, breathing difficulties, pneumonia and seizures.