22-03-20, 20:05
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#11
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Join Date: Feb 2011
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re: COVID-19 >Vaccine Ready by Sept & Yr Fever PROTECTS Your Immune System
UPDATE:
& REMEMBER > Cleanliness is Next to Godliness..
PLEASE dont allow the crazy media to cause you more anxiety folks... Modern Science has well advanced since the last serious epidemic..>
Coronavirus Vaccine Trials Begin at UK's Secret Science Base on Animals and Humans
Scientists will test the drug on animals at the Wiltshire base before trialling on humans, bring together the same expertise that was successfully used in supporting the development of the Ebola vaccine, licensed in 2019
The Guardian UK / Daily Mirror UK, 22 MAR 2020
The development of a vaccine against coronavirus is edging closer as human and animal trials begin at the Government's secret science base
Scientists will test the drug, made at Oxford University, on animals at the Wiltshire base before trialling on humans next month.
In recent years, this expertise has been successfully used in supporting the development of the Ebola vaccine, licensed in 2019.
Public Health England's (PHE) Porton Down researchers have collaborated with colleagues at UK Liverpool and Bristol universities to develop ‘synthetic virus’ – an exact replica of the actual virus for use in the laboratory.
This will enable them to carry out rigorous evaluation and testing of vaccines and treatments that enter the clinic.
The Times reports that the Phase II trials will begin before the results of the animal trials are known, as the Crisis lurches into its next, dramatic phase.
Normally, larger Phase III trials are needed before a drug is clinically approved. In emergencies, however, such trial vaccines are released early for key workers.
The Oxford drug is one of multiple such proto-vaccines in development worldwide, as the number of positive tests worldwide exceeded 200,000
Prof Robin Shattock, from Imperial College London, told the BBC's World at One yesterday: "The first part of testing is to check that it's safe in humans in small numbers, and again induces the right sort of immune response.
"hat will take, even if we do things quickly, two to three months.
"The next stage would be to ramp it up and start looking at whether the vaccine actually can prevent infection in the community.
"You need to produce the data to show a vaccine works and how well it works before you can get a licence to sell that as a product."
Scientists hope the vaccine - which contains a section of genetic code from the coronavirus - will train the body to attack the virus.
Prof Miles Carroll, Deputy Director, National Infection Service, Public Health England, said: Public Health England is uniquely positioned to support and drive the country’s hunt for a coronavirus vaccine – using tried and tested methods for the rapid development of interventions for emerging diseases.
We look forward to continuing to work with world-leading academic and pharmaceutical partners to accelerate progress towards safe and effective interventions to limit the impact of this new infection as rapidly as possible.
Lord Bethell, Minister of Innovation, said: "It makes me so proud to see PHE Porton Down demonstrate its world-beating expertise with this US FDA award.
It is a powerful testimony to the expertise and commitment of the remarkable PHE team at this historic site."
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