St. Louis Rams: 125-1
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These are not the St. Louis Rams that went 7-9 last year and almost won their division.
This team more closely resembles the older Rams team, specifically the one that did badly enough to get the number one overall pick and select Sam Bradford. The team this year has suffered from injuries to key players. Steven Jackson has missed some playing time and Bradford has been a bit beaten up as well.
Even if the Rams do get their offense working, they've already gone down to 0-4. They won't win a Super Bowl this year.
Overall Odds: 125-1