Indianapolis Colts: 200-1
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Look, we all know that the Colts are going to manage maybe two wins this year if Peyton Manning doesn't get back on the field. The team hasn't ruled out Peyton's return, which is currently scheduled for mid-December or so.
Of course, just as likely is that Peyton's injury will wind up being a career-ender. With no one to take Peyton's place, they don't stand a chance of making the playoffs or the Super Bowl. This one just ain't gonna happen. The odds are infinitely small. Or said another way...
Overall Odds: "one for each star in the sky"-1