Chicago Bears: 35-1
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The Bears and Bills are kind of the opposite sides of the same coin. The Bills have strong offense and a questionable defense. The Bears have a strong defense powered by Julius Peppers, and no passing game.
Seriously, their only offensive weapon to help Jay Cutler is Matt Forte. Forte leads the team in receptions and rushed for over 200 yards and a touchdown during Week 4. Of course, good teams can stop a running back, and if teams can stop Forte, the Bears defense likely isn't dominant enough to keep the hounds away forever.
I'd say this team has a 35-1 chance of taking home the Lombardi Trophy in January of 2012.