Carolina Panthers: 100-1
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I know that the NFL is a passing league, but really, you still need a good overall team effort to win games. Unfortunately for the Panthers, they don't have a good team.
Their offensive line is doing a great job of pass protecting, but they've become enamored of Cam Newton's arm and are completely one-dimensional on offense. It's not a good thing, because playoff quality teams, especially if they catch a whiff of January, will have the players to stop the one thing a bad team does best.
It also doesn't help that they're currently 1-3.
Overall Odds: 100-1